Enter LC50 Values for Raw Materials
This is a brief guide to entering LC50 values for raw materials on to Formpak to facilitate mixture calculations for inhalation toxicity relating to GHS and Safety Data Sheets.
Background in GHS
GHS refers to different types of airborne ‘stuff’: gases, vapours, dusts/mists. The units in GHS for these different forms are gases ppmV, vapours mg/l and dusts/mists mg/l.
The calculation to estimate the ATE Inhalation requires the airborne form and the units are consistent with GHS.
The LC50 data available in literature and from suppliers can be presented in different units. So, when adding LC50 data into Formpak you need to know what type of airborne form the data relates to and check the units used. If required, you need to convert values to be consistent with the units used in GHS.
In the calculation of inhalation toxicity of a mixture:
Note:The ATE is set around the 10th percentile in the range for the category, so conservatively low but not the worst case.
Enter LC50 Data for Raw Materials into Formpak
1. If you have LC50 data, check:
2. In Formpak, for the raw material (at regulatory level*):
Example Raw Material with an LC50 of 5.1 for Vapour route